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For instance, the GLP-1 receptor agonist exendin-4 (Ex-4) attenuates astrocytic production of inflammatory factors, including vascular endothelial growth factor A (VEGF-A), matrix metalloproteinase-9 (MMP-9), CCL2, and C-X-C motif chemokine ligand 1 (CXCL-1) (312)