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The role of iron metabolism in lung inflammation and injury

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Results: At Week 96, 24 of 88 (27%) participants (TAF 8, PLB-TAF 9 in Cohort 1

Previously, a study based on proteomic analysis had revealed marked transcriptional repression of other Nrf2-induced antioxidant proteins including CK2, ERK1/2, PKC, GPx, Mgst1, peroxiredoxin 3 (Prdx3), in both preclinical models and in human spinal MNs from ALS patients [253]