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doi: 10.1016/j.immuni.2015.03.005 48 SasoYConnerEMTeegardenBRYuanCS

775 An acidic pH in the TME can reduce the antigen-presenting capability of dendritic cells, impairing T-cell activation

With respect to the treatment of neurodegenerative diseases, the general pro-survival anti-apoptotic activity of HGF supports the use of HGF mimetics for treating neurodegenerative diseases including but not limited to Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis (ALS), etc