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This process occurs naturally when the olives mature, as well as artificially during the storage and processing of table olives [42]

Furthermore, studies suggest that these alkaloids may also directly induce programmed cell death in neurons and glial cells via activation of the PPAR/NF-B/caspase-3-dependent apoptotic pathway, offering a novel explanation for their potential long-term or subacute neurotoxic effects [42]

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Increased activation in the striatum and insula is beneficial for movement-related learning and attention control (Ji et al., 2017)