glutathione reaction disulfide File:Disulfide Bond Formation.jpg Redox Regulation by Protein S-Glutathionylation:

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In all the above examples, the additional Cys is the resolving Cys, suggesting the reactive Cys must come first in order for the mutation to become fixed in the population

8 This supports catecholaminergic models of the disorder, which propose that disrupted dopamine and noradrenaline signaling in frontostriatal and prefrontal circuits contributes to the attentional, motivational, and inhibitory control deficits characteristic of ADHD

Current knowledge about the underlying mechanisms of reductive stress and its biological consequences as well as how cells respond to reductive stress remains limited