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While this process is important for detoxification of the parent compound, which is often highly reactive, GSH conjugation also irreversibly consumes intracellular GSH (199)

Although cysteine deprivation activates the ISR 14 , contribution of GSH to the regulation of the stress response remains largely unknown

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Certain gut bacteria, such as Escherichia coli and Bacillus subtilis , produce amyloid-like proteins that can cross-seed with endogenous amyloid proteins in the brain, potentially contributing to neurodegenerative conditions like Parkinsons and Alzheimers diseases [158]