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(Scientific Reports, 2021) reported that NNMT inhibition plus a lean-diet substitution lowered body weight, fat mass, and liver fat beyond either intervention alone

Pathway-Focused Metabolic Research : Exploring how AOD 9604 influences -adrenergic-linked pathways and AMPK activity, both of which regulate cellular energy status and lipid metabolism

A recent screening-based study has identified several promising SARM1 inhibitors, including non-competitive inhibitors such as berberine chloride and zinc chloride 233 , suggesting the presence of an allosteric binding pocket that can be targeted for therapeutic development