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SOD1 is a dimeric, while SOD2 and SOD3 are tetrameric

Interestingly, earlier studies did not report an absolute decline in either GSH or GSSG in mature PK-deficient erythrocytes, but a decline in GSH/GSSG ratio was reported to result in an acquired reduction in PK-activity ( via the TCA cycle ( As described in section I, Reticulocyte features in PKD: historic observations , earlier observations showed that (non-maturing) young reticulocytes in PKD are degraded by the red pulp macrophages of the spleen

Padayatti PS, Leung JH, Mahinthichaichan P, Tajkhorshid E, Ishchenko A, Cherezov V, et al

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