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Description

The precise mechanism behind the hypertrophy and hyperplasia of ASM induced by obesity remains insufficiently understood

l , Immunoblot of indicated proteins in HeLa cells treated with erastin (5 M) and co-treated with either GSH (10 mM), GSHee (10 mM), Trolox (50 M) or Ferrostatin-1 (5 M) for 48 h

As expected GPP3 was observed bound within the hydrophobic pocket of VP1, in an essentially identical conformation to that previously observed for this compound bound to plant expressed PV3-SC8 18 (Fig