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At the same time, calcium overload promotes the decomposition of complex II in the respiratory chain by binding to cardiolipin in the inner mitochondrial membrane (IMM), leading to the release of various subunits, resulting in the production of large amounts of reactive oxygen species (ROS) and ultimately causing cell apoptosis [92]

Desmaris et al., 2018)

What began as subtle shifts in how clothes fit becomes obvious changes in the mirror

2023) and proton magnetic resonance spectroscopy studies implicating glutamate abnormalities as well as increased levels of neuroinflammation in some patients (Filatova et al