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Available online at: StatPearls

While acne is primarily influenced by factors like hormones and genetics, there is evidence to suggest that obesity can indirectly contribute to acne development

This creates a unique demand that cannot be met by other amino acids

As the primary source of reducing equivalents, NADPH is primarily produced by glucose-6-phosphate dehydrogenase (G6PD) and 6-phosphogluconate dehydrogenase in the pentose phosphate pathway (PPP)