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Description

SYK knockdown in the AMAN model resulted in diminished expression of the regeneration-associated SC marker c-Jun, impaired axonal regrowth (NF200) and delayed remyelination (MBP), fewer myelinated axons, increased g-ratios, exacerbated muscle atrophy, and severe functional deficits, including reduced CMAP amplitude, increased latency, and worsened gait

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Index primers (NEBNext Multiplex Oligos for Illumina, New England Biolabs) were incorporated by PCR, and indexed fragments of interest were adsorbed using 1.2 volumes of AMPure XP beads

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