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On the other hand, tumor cells suppress Akt signaling in CD8 + T cells via the PD-L1/PD-1 axis, promoting GATA1 nuclear translocation and downregulating PLPP1 expression

However, keep in mind this benefit was seen in animals and has not yet been studied in humans

[DOI] [PMC free article] [PubMed] [Google Scholar] 44.Leffler DA, Kelly CP, Green PHR, Fedorak RN, DiMarino A, Perrow W, Rasmussen H, Wang C, Bercik P, Bachir NM, Murray JA