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However, this impaired regeneration can be restored through in vivo blockade of the IFN-I pathway

Previous researchers found that activating mTOR promoted the invasion and metastasis of cancer [28, 29]

Acknowledgments The authors would like to acknowledge the research team in the Center for Tissue Engineering and Regenerative Medicine (CTERM), Faculty of Medicine, Universiti Kebangsaan Malaysia for the technical support throughout this review