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Increased levels of ROS and lower expression of glycolysis-associated genes, including glucose transporter-1 (GLUT1), phosphofructokinase (PFK), and lactate dehydrogenase A (LDHA), have been reported in granulosa cells of PCOS women compared with non-PCOS women, indicating that the low oocyte competence in PCOS may be associated with mitochondrial dysfunction and abnormal glycolysis [40]