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The procognitive effect was then traced to the hepatocyte growth factor system and its receptor c-Met, with the synaptogenesis reported as dependent on HGF/c-Met activation (Benoist et al., J Pharmacol Exp Ther 2014)

167 These signal molecules and the partners with which they interact intracellularly are involved in the regulation of early embryonic development, cell proliferation, adhesion, polarity, cytokinesis, and survival