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This deletion variant has been associated strongly with susceptibility to bladder cancer [13], multiple sclerosis [14] and early onset of severe mental disorders [15], among other diseases

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dsDNA (200 ng/L) was incubated for 2 and 72 h at room temperature (25 1C), in either presence or absence of ascorbic acid (50 and 1,000 M) at both intrinsic and neutral pH