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Expression and activity are modulated by genetic polymorphisms, xenobiotics, cytokines, hormones, sex, age, and disease states ( 2.1.1 CYP1 family The human CYP1 gene family comprises CYP1A1, CYP1A2, CYP1B1, and the pseudogene CYP1D1P ( 2.1.2 CYP 2 family The CYP2 family, which includes isoforms such as CYP2A6, CYP2B6, CYP2C8, CYP2C9, CYP2C19, CYP2D6, and CYP2E1, plays a crucial role in the metabolism of drugs and endogenous compounds

Rossetto and Pari, 2014) is likely to be an overture that will be followed by a new chapter of regulation of viral latency and reactivation by non-coding RNAs, both viral and cellular

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