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Furthermore, our understanding of environmental carcinogens continues to evolve, and future directions for research should include the mechanisms driving carcinogenesis mediated by non-tobacco-related exposures, such as environmental pollution, and their interaction with underlying germline variation

The risk of bleeding is especially high in those who are elderly, had a recent stroke or surgery, have uncontrolled hypertension, or have a bleeding tendency, and is compounded in those who regularly use anticoagulant medications

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