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On average, 6% to 30% of people taking metformin may have vitamin B12 deficiency

This can cause a wide variety of issues, including brain fog, low energy, and physical signs of aging

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This approach ensures that the nanomaterial will be activated primarily in the vicinity of pathogenic bacteria, which thrive in such environments and will remain inactive in the more neutral pH of healthy tissues, pH-responsive NPs are commonly made using materials like chitosan, which undergoes protonation in acidic conditions, leading to a release of encapsulated drugs or antimicrobial agents at infection sites