chac1 glutathione CHAC1: a master regulator of oxidative stress and ferroptosis in human diseases and cancers BACH1–CHAC1–Glutathione Axis Aggravates Myocardial Ischemia–Reperfusion

BACH1CHAC1Glutathione Axis Aggravates Myocardial IschemiaReperfusion Injury by Enhancing Ferroptosis and Oxidative Stress Identification of Juglone, a 'first in class' inhibitor of the human glutathione degrading enzyme, ChaC1, using yeast based high throughput screens bioRxiv Glutathione specific gammaglutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis Science Translational Medicine L 2 Hydroxyglutarate sensitizes ferroptosis through ATF3 CHAC1 mediated glutathione degradation in hepatocellular carcinoma Cell Death & Disease

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