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[Crossref] [PubMed] Parisi S, Polishchuk EV, Allocca S, et al

Posttranslational modification and mutation of histidine 50 trigger alpha synuclein aggregation and toxicity

It has also been found that Keap1/Nrf2 mutation status predicts the risk of local recurrence after radiotherapy in NSCLC patients, and Keap1/Nrf2 mutant lung cancers may be radiotherapy resistant to radaition due to enhanced expression of ROS clearance and detoxification pathways (Umamaheswari et al., 2021)