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Thus, it is urgent to advance our knowledge regarding subretinal fibrosis and its pathogenic mechanisms to develop alternative therapeutic options

In conclusion, in a meta-analysis of four studies, which included 259 AD patients and 307 healthy controls, it was observed that AD patients had significantly lower serum vitamin E levels than the control group (standardized mean difference: -1.08, 95% CI: 1.80 to 0.36) (81)