6 Therapeutic strategies targeting oxidative stress in DR As discussed in the previous sections, oxidative stress plays a pivotal role in the pathogenesis of DR
( B H ) Results from the insulin clamp: average leg glucose uptake ( B ), prior exercise-induced change in leg glucose uptake () ( C ), average leg blood flow ( D ), prior exercise-induced change in blood flow () ( E ), average blood glucose A-V difference ( F ), prior exercise-induced change in AV glucose difference () ( G ), and whole-body glucose clearance ( H )
Focus on a balanced, anti-inflammatory diet, regular movement, quality sleep, and stresssupporting nutrients (learn more about this in our guide to antiaging supplements)
The altered activity of a biomarker may result from, for example, altered biomarker expression, altered biomarker protein levels, altered biomarker structure, or, for example, altered interaction with other proteins involved in the same or different pathways as the biomarker or altered interaction with a transcription activator or inhibitor