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[DOI] [PubMed] [Google Scholar] 93.Coughlin JM, Ishizuka K, Kano SI, Edwards JA, Seifuddin FT, Shimano MA, et al

The beneficial improvement in the metabolic profile mediated by MD-1 treatment in HFD animals is comparable to that of standard metformin

257 In mouse models with a mutated superoxide dismutase (SOD1) gene (G86R), p53 transcriptional activation and alterations in Bcl-x/Bax ratio were observed