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It improves cell viability in neuron and microglia co-culture systems by inhibiting the NLRP3 inflammasome and stimulating SIRT1 signaling [188]

Ravelli, G.-P., Stein, Z

When compared with the other H 2 O 2 scavenger enzymes, CAT seems to be the key enzyme to remove high intracellular concentrations of H 2 O 2 [32, 53, 59, 60]