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iScience 27 , 110359 (2024)

2019 May 27;3(2):200-214

Moreover, inhibition of mGluR5 was shown to enhance the potency of chemotherapeutic agents in hepatocellular carcinoma cell lines and attenuate chemotoxicity over DNA damage by downregulating Ca 2+ -dependent MAPK signaling in the normal liver (76)

If being solely relied upon due to an absence of intrinsic factor, much higher doses of B12 are required than can be found in animal foods, fortified foods, or multivitamins