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Chronic IH may also result in an imbalance in the ratio of arginase-1 (an enzyme that competes with eNOS for L-arginine) to eNOS expression, resulting in decreased NO availability, a key feature of ECD [149]

Body specific substance It is not an essential nutrient because our body can make it itself from its constituent substances

Stimulation Assays Ipamorelin is added to the cultured cells at various concentrations, and the release of growth hormone (GH) is measured over time

Acknowledgements The authors appreciate and thank the efforts of the Center for the Development of Clinical Researches of the Educational and Therapeutic Research Complex of Birjand University of Medical Sciences