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Serine biosynthesis with one carbon catabolism and the glycine cleavage system represents a novel pathway for ATP generation

4) 35,36,37 , which can subsequently be transaminated to form glycine

It is tempting to speculate, however, that the ROS-producing reaction may contribute to the long-term stability of SOD1 by preserving the oxidized status of its conserved disulfide in a highly reducing atmosphere of cellular interior