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Dicoumarol sensitizes hepatocellular carcinoma cells to ferroptosis induced by imidazole ketone erastin

Even the overall expression of cyclins (Cyclin D, Cyclin E, CDK 4, CDK 1, and PCNA) was down-regulated in time-dependent increasing concertation of the EGCG-treated group as compared to the untreated control group by Western blot analysis that blocked the G1 phase of the cell cycle [47]