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Description

Locomotion is increased in A11-lesioned mice with iron deprivation: a possible animal model for restless legs syndrome

After surgery, patient follow-up was conducted on a weekly basis for the initial two months and monthly thereafter for 1355 months

These murine models were then presented with methylprednisolone (corticosteroid)

SPIGFD in these patients were defined by phenotypic and biochemical characteristics and they were treated with recombinant human (rh)IGF-1 in one of the clinical trials leading to approval of this therapy, as described later