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However, CTX is associated with significant reproductive toxicity, which adversely affects the reproductive health of patients undergoing chemotherapy for breast cancer 10,11,12

A growing body of research suggests low-dose colchicine (generally 0.5 mg per day) may reduce the risk of blood clot-related cardiovascular events such as heart attack and strokeespecially when used in conjunction with other standard cardiovascular medicationsthrough its ability to reduce inflammatory signaling in blood vessels

10.1016/j.freeradbiomed.2017.01.027 74

Fox M, Mills AM, Ramgopal M, Bettacchi CJ, Osiyemi O, Hinestrosa F, et al