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Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer

CD117 is a tyrosine kinase receptor, and peritoneal fluid obtained from patients with OC having CD117+ cells can form tumors with the same self-renewal and differentiation capacity as cells derived from the tumor (68)

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Because the level of acetaminophen at the time of the predetoxification assay may not be a peak value (peak may not be achieved before 4 hours post-ingestion), obtain a second plasma level in order to decide whether or not the full 17-dose detoxification treatment is necessary