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Chronic venous insufficiency (CVI) occurs when leg veins cant effectively return blood to the heart

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[DOI] [PMC free article] [PubMed] [Google Scholar] 32.N-acetylcysteine for treating cocaine addiction - a systematic review

The same applies to oral vitamin C bioavailability is roughly 3050% from oral doses, compared with near-100% intravenously, and blood concentrations achievable via IV simply cannot be reached orally