glutathione pyruvate dehydrogenase Scheme showing the enzymatic reactions that catalyze the Mitochondrial hydrogen peroxide production by

Deboever N, Bayley EM, Feldman HA, Hofstetter WL, Mehran RJ, Rice DC, Rajaram R, Roth JA, Sepesi B, Swisher SG, Vaporciyan AA, Walsh GL, Bednarski BK, Morris VK, Antonoff MB

Levels of multiple intracellular nutrients (iron, selenium, vitamin E and coenzyme Q10) are intimately related to the cellular antioxidant system and participate in the regulation of ferroptosis

Jan, Stanford University, United States Reviewed by Eric Bielefeld, The Ohio State University, United States

Studies demonstrate that oxidative stress is a significant factor in the occurrence of numerous types of cardiovascular conditions, including atherosclerosis, myocardial infarction, hypoxia, hypertension, and atrial fibrillation