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Taking them improperly or for too long can lead to receptor desensitization , meaning your body may stop responding over time

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In turn, LATS1/2 phosphorylate YAP/TAZ to inactivate them, promoting their cytoplasmic localization [86]

However, dietary polyphenols are typically found in low quantities in foods and exhibit low bioavailability, largely due to poor stability and solubility 7