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AOD-9604 works by stimulating lipolysis, the breakdown of fats and triglycerides, and inhibiting lipogenesis, the formation of new fat

The compound has been investigated in adipocyte-research and metabolic-disease research contexts where elevated NNMT activity has been linked to insulin resistance and adipose-tissue dysfunction

For CY 2026, we are applying the previously finalized reduction to the OPPS conversion factor under 419.32(b)(1)(iv)(B)(12) used to determine the payment amounts for non-drug items and services for hospitals for whom this adjustment applies of 0.5 percent

Its characterization and evaluation are limited exclusively to controlled laboratory research environments