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Furthermore, a recent case-control study from the NIH, which reviewed 110 PD cases and 358 controls, and observed that PD incidence was increased 2.5 times in individuals who reported use of rotenone compared with nonusers [17]

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In contrast to zinc deficiency, which is often a consequence of inadequate intake or absorption, zinc excess typically arises from deliberate dietary oversupplementation or environmental contamination [151]