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10.1152/ajpheart.00305.2002 39 HoJ

The water becomes the single unverified link in an otherwise verified chain

In a systematic review and meta-analysis, depression was associated with significantly increased oxidative stress as measured by biomarkers of oxidative DNA damage (8-OHdG) and lipid peroxidation (F-isoprostanes) compared to non-depressed controls (3537)