gary klow obituary K Archives Gary Wayne Clow Obituary (2023)

The SIRT2/cMYC pathway inhibits peroxidation-related apoptosis in cholangiocarcinoma through metabolic reprogramming

H., Michopoulos V

Before being peroxidized, PUFAs are thioesterified by acyl-CoA synthetase long-chain family member 4 (ACSL4) and then combined with phospholipids to integrate into the plasma membrane by lysophosphatidylcholine acyltransferase 3 (LPCAT3), finally polyunsaturated fatty acyl moieties present on phospholipids (PL-PUFAs) are formed

Mutations in CFTR, which form the basis for the clinical manifestations of cystic fibrosis, affect the epithelial innate immune function in the lung, resulting in exaggerated and ineffective airway inflammation that fails to eradicate pulmonary pathogens