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doi: 10.1016/j.it.2025.02.015 24 LamWYBhattacharyaD

IGF-1 is broadly implicated in cell proliferation, extracellular matrix organization, angiogenic signaling, and tissue regeneration, which is why GH-axis stimulation is frequently studied in relation to repair processes

In addition, Okabayashi et al

The SBR was calculated as SBR = fluorescence intensity (or chemiluminescence intensity)/background, where background is the signal intensity of the adjacent tissue acquired during imaging