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A reduction in GLS1 RNA expression upon cystine deprivation in Hs578T cells was previously reported by Bottoni et al

Stem Cells

[3] Jastreboff, A.M., et al

RAS/MAPK is one of the dominant cancer-initiating pathways and has a well-known impression in tumorigenesis by enhancing the survival and metastasis of cancer cells [115]