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This necessitates therapeutics and sensors with stability, intelligence, and multifunctionality

Initiation and propagation of alpha-synuclein aggregation in the nervous system

The cell initiates apoptotic death when it senses that its environment of physical state has been vigorously compromised

While cytosol, peroxisomes, mitochondria, and plastids in Arabidopsis wild-type plants maintain a highly reduced glutathione buffer with redox potentials of less than 310 mV, the ER is far less reducing with E GSH values of less than 240 mV (Meyer et al., E GSH with high specificity due to selective mediation of thiol/disulfide exchange reaction between glutathione and roGFP by GRXs (Meyer et al., E GSH is outside the measuring range of these probes thus limiting their usability