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For each applicable calendar quarter and for each Part B rebatable drug by billing and payment code, we proposed to use the payment amount in the payment amount benchmark quarter (per 427.302(d)), benchmark period CPI-U (per 427.302(e)), and rebate period CPI-U (per 427.302(f)) to identify the inflation-adjusted payment amount

Once demyelination is complete the amount of activated RCA-1 (RCA, Ricinus communis agglutinin-1)/Mac-3-positive microglia starts to decrease (Mason et al., 2004