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Availability: InStock
Rating: 4.7281 (27 reviews)

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Description

This epigenetic modification suppresses SLC7A11 transcription, thereby reducing xCT expression, impairing cystine uptake, and limiting intracellular GSH synthesis, ultimately heightening neuronal vulnerability to ferroptosis (92)

TABLE 3 Comparing the advantages and disadvantages of different ferroptosis inhibition methods

Brain tissue is particularly vulnerable to OS and highly susceptible to oxygen radical damage because of its high oxygen consumption and lack of antioxidant enzymes