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Taken together, preclinical and clinical studies in neuroblastoma suggest the potential for BSO to enhance L-PAM activity against diseases that use myeloablative dosing of L-PAM and previous investigations with one murine plasmacytoma, 17 and a human MM cell line, 8, 10 demonstrated enhanced activity of L-PAM by BSO

CircRUNX1 also accelerates lung adenocarcinoma cell proliferation and metastasis by targeting the miR-5195-3p/HMGB3 pathway [194]

Activated NOXs produce superoxide radicals that are converted by the SOD-catalyzed dismutation reaction to hydrogen peroxide

Pharmacological activation of GPX4 by selenomethionine attenuates cisplatin-induced ototoxicity and hearing loss