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Current treatment modalities and limitations Pharmacological treatment remains the primary current approach to managing PD, with levodopa considered the gold standard for alleviating motor symptoms 51

Additionally, it helps produce DNA and RNA

Moreover, the dynamic communication of L-Phe at its predicted binding site in the hinge region with the Ca 2+ binding sites not only influences the adjacent Ca 2+ binding site 1, but also globally enhances cooperative activation of the receptor in response to alterations in extracellular Ca 2+