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Supplementation with alternative treatments like folinic acid has demonstrated improvements in quality of life for many of these individuals

MS spectra were acquired between 3501,250 m/z (molecular weight/valency) in high-resolution mode (40,000 resolution for full scans and 20,000 resolution for MS/MS scans) with a rolling collision energy using a 250 ms accumulation time/spectrum and 50 mDa mass tolerance, and the 10 most intense precursors per cycle were selected for fragmentation with a dynamic exclusion time of 30 s

Participants consuming the spermidine supplement had moderately enhanced memory performance after three months compared to those who took the placebo

However, they do carry risks of side effects and complications