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Exercise-induced lactate activates G protein-coupled receptor 81 (GPR81), also known as hydroxy carboxylic acid receptor 1 and a selective lactate-sensing receptor, which is downregulated under atherogenic OS

This patient's history of recurrent pancreatitis, profound weight loss, and distinctly oily, foul-smelling stools point to pancreatic exocrine failure rather than a brush border enzyme deficiency

The result is a state-of-the-art, market-ready cold storage facility designed to support fast-moving, temperature-controlled operations

IR induces ferroptosis in ovarian granulosa cells, associated with elevated iron levels and decreased GSH levels and GPX4 activity [53]