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Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, et al

In the cytosol, methylcobalamin becomes the cofactor for methionine synthase (encoded by MTR ), which remethylates homocysteine to methionine using a methyl group donated by 5-methyltetrahydrofolate

(JCEM 2006) conducted two randomized, double-blind, placebo-controlled trials in 57 healthy adults (ages 2161)

Martn-Rivada , Cambra Conejero A, Martn-Hernndez E, Moris Lpez A, Blanger-Quintana A, Caedo Villarroya E, Quijada-Fraile P, Bellusci M, Chumillas Calzada S, Bergua Martnez A, Stanescu S, Martnez-Pardo Casanova M, Ruz-Sala P, Ugarte M, Prez Gonzlez B, Pedrn-Giner C